18 Chicken breast recipes casserole

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Chicken breast casseroles are hearty, comforting, and versatile — perfect for family dinners, meal prep, or cozy weekends.

These 18 delicious casseroles transform simple chicken breasts into warm, satisfying meals filled with creamy sauces, melted cheese, and rich flavors.

1. Chicken and Rice Casserole

Tender chicken, fluffy rice, and a creamy mushroom sauce come together in this comforting classic that’s perfect for busy weeknights.

The flavors meld beautifully, creating a cozy and filling dinner everyone will love.

Ingredients:

  • 2 chicken breasts, cubed

  • 1 cup long-grain rice (uncooked)

  • 1 can cream of mushroom soup

  • 1 ½ cups chicken broth

  • 1 small onion, chopped

  • 1 cup shredded cheddar cheese

  • Salt and pepper to taste

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Combine rice, soup, broth, and onion in a greased baking dish.

  3. Add chicken and season with salt and pepper.

  4. Cover with foil and bake for 45 minutes.

  5. Remove foil, sprinkle cheese on top, and bake another 10 minutes.

2. Broccoli Chicken Casserole

Creamy and cheesy, this casserole blends juicy chicken with tender broccoli florets for a wholesome and flavorful family favorite.

It’s a great way to get your greens while still indulging in comfort food.

Ingredients:

  • 2 chicken breasts, cooked and shredded

  • 2 cups fresh broccoli florets

  • 1 can cream of chicken soup

  • 1 cup sour cream

  • 1 cup shredded cheddar cheese

  • ½ cup breadcrumbs

  • 1 tbsp butter, melted

Instructions:

  1. Preheat oven to 350°F (175°C).

  2. Mix soup, sour cream, and half the cheese in a bowl.

  3. Stir in broccoli and shredded chicken.

  4. Pour mixture into a casserole dish and top with remaining cheese.

  5. Mix breadcrumbs with butter, sprinkle on top, and bake 30 minutes.

3. Chicken Alfredo Casserole

This creamy Alfredo pasta bake combines tender chicken, penne, and rich sauce for an irresistible comfort meal that’s both elegant and easy.

Ingredients:

  • 2 chicken breasts, cooked and diced

  • 12 oz penne pasta, cooked

  • 2 cups Alfredo sauce

  • 1 cup mozzarella cheese

  • ½ cup grated Parmesan

  • 1 tbsp parsley, chopped

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Mix pasta, chicken, Alfredo sauce, and half of the cheese.

  3. Spread mixture into a baking dish and top with remaining cheese.

  4. Bake for 20–25 minutes until bubbly and golden.

  5. Sprinkle parsley before serving.

4. Chicken and Spinach Casserole

Fresh spinach and tender chicken are baked in a creamy sauce with melted cheese for a light yet satisfying dinner option.

Ingredients:

  • 2 chicken breasts, sliced

  • 3 cups fresh spinach

  • 1 can cream of mushroom soup

  • ½ cup milk

  • 1 cup mozzarella cheese

  • 1 tsp garlic powder

Instructions:

  1. Preheat oven to 350°F (175°C).

  2. Mix soup, milk, and garlic powder together.

  3. Layer spinach and chicken in a greased dish.

  4. Pour sauce over top and sprinkle cheese.

  5. Bake for 30 minutes until hot and golden.

5. Chicken Enchilada Casserole

All the zesty Mexican flavors you love in enchiladas are layered into a cheesy, saucy, and crowd-pleasing casserole.

Ingredients:

  • 2 cups cooked, shredded chicken

  • 1 can enchilada sauce

  • 8 corn tortillas, halved

  • 1 cup shredded cheddar cheese

  • ½ cup sour cream

  • 1 can black beans, drained

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Layer tortillas, chicken, beans, and enchilada sauce in a casserole dish.

  3. Repeat layers and top with cheese.

  4. Bake for 25 minutes until bubbling.

  5. Serve with sour cream and fresh cilantro.

6. Chicken Parmesan Casserole

A baked twist on the Italian classic, this dish layers crispy chicken, tangy marinara, and melted cheese for a mouthwatering family favorite.

Ingredients:

  • 2 chicken breasts, cubed

  • 1 jar marinara sauce

  • 1 cup mozzarella cheese

  • ½ cup grated Parmesan

  • 1 cup breadcrumbs

  • 1 tbsp olive oil

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Spread chicken in a baking dish and top with marinara.

  3. Mix breadcrumbs with olive oil and sprinkle over top.

  4. Add cheeses and bake for 30 minutes until bubbly and golden.

7. Cheesy Chicken and Potato Casserole

Warm, creamy, and full of flavor, this casserole combines diced potatoes and chicken in a rich cheese sauce.

Ingredients:

  • 2 chicken breasts, cubed

  • 3 cups diced potatoes

  • 1 can cream of chicken soup

  • 1 cup sour cream

  • 1 cup cheddar cheese

  • Salt, pepper, and paprika to taste

Instructions:

  1. Preheat oven to 400°F (200°C).

  2. Mix soup, sour cream, and cheese in a bowl.

  3. Stir in potatoes and chicken, season well.

  4. Pour into a greased dish and bake for 40 minutes.

8. Chicken and Stuffing Casserole

A cozy dish that combines creamy chicken filling with buttery stuffing for the perfect homestyle meal.

Ingredients:

  • 2 chicken breasts, shredded

  • 1 box stuffing mix

  • 1 can cream of chicken soup

  • ½ cup sour cream

  • 1 cup chicken broth

Instructions:

  1. Preheat oven to 350°F (175°C).

  2. Mix soup, sour cream, and chicken.

  3. Spread in a baking dish and top with stuffing.

  4. Pour broth evenly over stuffing.

  5. Bake for 30 minutes until crisp on top.

9. Buffalo Chicken Casserole

Spicy, creamy, and cheesy, this casserole delivers all the bold buffalo wing flavors in an easy baked dish.

Ingredients:

  • 2 cups shredded chicken

  • ½ cup buffalo sauce

  • 1 cup ranch dressing

  • 1 cup mozzarella cheese

  • 2 cups cooked pasta or cauliflower

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Mix chicken, buffalo sauce, ranch, and pasta.

  3. Spread in a baking dish, top with cheese, and bake 25 minutes.

10. Chicken Bacon Ranch Casserole

This creamy, cheesy casserole brings together chicken, smoky bacon, and tangy ranch dressing for a rich, satisfying dinner.

Ingredients:

  • 2 chicken breasts, diced

  • 1 cup cooked bacon, crumbled

  • 1 cup ranch dressing

  • 2 cups cooked pasta

  • 1 cup cheddar cheese

Instructions:

  1. Preheat oven to 350°F (175°C).

  2. Combine all ingredients and pour into a baking dish.

  3. Bake for 25 minutes until hot and cheesy.

11. Chicken and Mushroom Casserole

Earthy mushrooms and tender chicken cook together in a creamy herb sauce, creating a dish that’s both comforting and elegant.

Ingredients:

  • 2 chicken breasts, sliced

  • 2 cups mushrooms, sliced

  • 1 can cream of mushroom soup

  • ½ cup milk

  • 1 tsp thyme

Instructions:

  1. Preheat oven to 350°F (175°C).

  2. Sauté mushrooms with thyme in butter.

  3. Mix soup and milk, pour over chicken in a baking dish.

  4. Add sautéed mushrooms and bake for 30 minutes.

12. Chicken and Zucchini Casserole

Packed with vegetables and melted cheese, this casserole is a lighter, low-carb way to enjoy creamy comfort food.

Ingredients:

  • 2 chicken breasts, diced

  • 2 zucchinis, sliced

  • 1 cup mozzarella cheese

  • 1 can cream of chicken soup

  • ½ cup sour cream

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Mix soup, sour cream, and chicken.

  3. Layer zucchini and pour mixture over it.

  4. Sprinkle cheese and bake for 25 minutes.

13. Chicken Tater Tot Casserole

Golden tater tots, creamy chicken filling, and melted cheese come together in this family-favorite comfort food.

It’s crispy on top, creamy inside, and always a hit at the dinner table.

Ingredients:

  • 2 cups shredded chicken

  • 1 can cream of chicken soup

  • 1 cup shredded cheddar cheese

  • 1 cup frozen peas and carrots

  • 2 cups frozen tater tots

  • Salt and pepper to taste

Instructions:

  1. Preheat oven to 400°F (200°C).

  2. In a bowl, combine soup, cheese, chicken, and vegetables.

  3. Spread the mixture evenly into a greased baking dish.

  4. Arrange tater tots on top in a single layer.

  5. Bake for 35–40 minutes until the tots are golden and crisp.

14. Chicken Fajita Casserole

All the spicy, sizzling flavors of chicken fajitas baked into one cheesy, satisfying casserole.

It’s colorful, bold, and perfect for a Mexican-inspired dinner night.

Ingredients:

  • 2 chicken breasts, sliced

  • 1 red bell pepper, sliced

  • 1 green bell pepper, sliced

  • 1 onion, sliced

  • 1 tbsp fajita seasoning

  • 1 cup shredded Monterey Jack cheese

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Toss chicken and vegetables with fajita seasoning.

  3. Spread mixture in a greased casserole dish.

  4. Top with cheese and bake for 25 minutes.

  5. Serve with warm tortillas or rice.

15. Chicken and Corn Casserole

A creamy, sweet, and savory bake that combines chicken, corn, and cheese for a simple but comforting dish.

Perfect as a hearty main or potluck side.

Ingredients:

  • 2 chicken breasts, shredded

  • 1 can cream-style corn

  • 1 cup whole corn kernels

  • 1 cup shredded cheddar cheese

  • ½ cup sour cream

  • ½ cup crushed crackers or breadcrumbs

Instructions:

  1. Preheat oven to 350°F (175°C).

  2. Mix corn, cheese, sour cream, and chicken in a large bowl.

  3. Pour into a baking dish and top with crackers or breadcrumbs.

  4. Bake for 30–35 minutes until golden and bubbly.

16. Chicken Noodle Casserole

This cozy dish turns classic chicken noodle soup into a creamy, cheesy bake that’s perfect for cold nights or quick weeknight dinners.

Ingredients:

  • 2 cups cooked egg noodles

  • 2 chicken breasts, cooked and shredded

  • 1 can cream of chicken soup

  • ½ cup sour cream

  • 1 cup shredded cheddar cheese

  • ½ cup peas and carrots

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Combine soup, sour cream, and cheese in a large bowl.

  3. Stir in noodles, chicken, and vegetables.

  4. Pour into a greased baking dish and bake for 25 minutes.

17. BBQ Chicken Casserole

Smoky BBQ sauce, melted cheese, and tender chicken make this casserole a delicious twist on barbecue night — no grill required.

Ingredients:

  • 2 chicken breasts, cooked and shredded

  • 1 cup barbecue sauce

  • 2 cups cooked pasta

  • 1 cup shredded mozzarella

  • ½ cup cooked bacon pieces

  • 1 small red onion, sliced

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Mix chicken, pasta, and barbecue sauce in a bowl.

  3. Spread mixture into a baking dish and top with cheese, bacon, and onion.

  4. Bake for 25–30 minutes until cheese is melted and bubbly.

18. Creamy Pesto Chicken Casserole

A fragrant and flavorful casserole featuring basil pesto, creamy sauce, and tender chicken breast — rich, cheesy, and bursting with Italian flair.

Ingredients:

  • 2 chicken breasts, sliced

  • ½ cup basil pesto

  • 1 cup heavy cream

  • 1 cup mozzarella cheese

  • ½ cup cherry tomatoes, halved

  • Salt and pepper to taste

Instructions:

  1. Preheat oven to 375°F (190°C).

  2. Whisk together pesto and cream.

  3. Arrange chicken and tomatoes in a baking dish, season lightly.

  4. Pour sauce over chicken and sprinkle with cheese.

  5. Bake for 25–30 minutes until bubbling and golden.

These 18 chicken breast casserole recipes make it easy to create comforting, crowd-pleasing meals with minimal prep and maximum flavor.

From creamy Alfredo to spicy fajita and classic rice casseroles, each dish brings warmth to the table — perfect for weeknights, holidays, or whenever you crave a hearty, homemade dinner.

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